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Corynebacterium Pseudotuberculosis Infection in Goats V.

Corynebacterium pseudotuberculosis infeksjon hos geit V. Relasjon mellom denne infeksjon og prosesser som følge av vaksinasjon mot paratuberkulose

Relationship Between the Infection and Lesions Resulting from Vaccination Against Para-Tuberculosis

Abstract

In 2 goat herds, one infected with Gorynebacterium pseudo-tuberculosis and one free from the infection,, goats were examined for superficial swellings on the shoulder and chest. All animals in this study had been vaccinated against paratuberculosis before the age of 4 weeks. The vaccine had been applied subcutaneously behind the shoulder. Twenty-two of 40 (55 %) and 31 of 45 (69 %) goats had such lesions in the infected and non-infected herds, respectively. The difference between the herds was not significant, P > 0.05.

Swellings found behind the shoulder in 19 goat carcasses derived from 4 herds in which G. pseudotuberculosis infection occurred were examined bacteriologically. No bacteria could be isolated from such lesions in 15 animals, while G. pseudotuberculosis in pure culture was isolated from 3 carcasses, and a mixed bacterial flora from the re-maining carcass. Bacteria could not be isolated from lesions situated behind the shoulder in 7 carcasses from 3 herds free from G. pseudo-tuberculosis infection.

It is concluded that most swellings on the shoulder and chest in goats were granulomas resulting from vaccination against paratuber-culosis.

Sammendrag

En undersøkelse over forekomst av overfladiske hevelser på bog og bryst ble foretatt på geifer i 2 besetninger, en med og en uten kaseøs lymfadenitt. Alle dyrene i disse besetningene var vaksinert mot paratuberkulose. Vaksinen var blitt applisert bak bogen på dyrene før 4 ukers alder. Det ble påvist slike hevelser hos 22 av 40 (55 %) under-søkte dyr i en besetning med kaseøs lymfadenitt og hos 31 av 45 (69 %) undersøkte dyr i en besetning fri for sykdommen. Forskjellen mellom besetningene var ikke signifikant, P > 0.05.

Det ble foretatt bakteriologiske undersøkelser av prosesser lokalisert like bak bogen fra 19 slakt fra ialt 4 besetninger med kaseøs lymfadenitt I prosesser fra 15 slakt ble bakterier ikke påvist. I prosesser fra 3 slakt ble Corynebacterium pseudotuberculosis isolert i renkultur, og i prosess fra ett slakt ble det påvist uspesifikk blandings-flora. Det ble ikke påvist bakterier ved undersøkelse av slike lesjoner fra 7 slakt fra 3 besetninger fri for kaseøs lymfadenitt.

Det konkhideres med at de fleste hevelser på bog og bryst var granulomer oppstått etter vaksinasjon mot paratuberkulose.

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Holstad, G. Corynebacterium Pseudotuberculosis Infection in Goats V.. Acta Vet Scand 27, 617–622 (1986). https://doi.org/10.1186/BF03548141

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