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Intracytoplasmic Inclusion Bodies Associated with Vesicular, Ulcerative and Necrotizing Lesions of the Digestive Mucosa of a Roedeer (Capreolus Capreolus L.) and a Moose (Alces Alces L.)

Intracytoplasmatiska inklusionskroppar associerade med vesikulära, ulcerativa och nekrotiserande lesioner i digestionskanalens slemhinnor hos et rådjur (Capreolus capreolus L) och en älg (Akes alces L)

Acta Veterinaria Scandinavica volume 28, pages 197–200 (1987)Cite this article

Abstract

At post-mortem examination of a roedeer and a moose, ulcerative and necrotizing lesions were observed in the digestive mucosa.

Both animals were serologically positive for Bovine Viral Diarrhea Virus antibodies. Histological examination revealed intra- and intercellular oedema in stratum germinativum and spinosum, formation of vesicles and ulcers, and intracytoplasmic inclusion bodies in numerous epithelial cells of mainly stratum germinativum.

Electronmicroscopy confirmed the histological findings and demonstrated inclusion bodies containing a granular electron dense material encircled by a single-layer membrane. Virus particles were not found.

Sammanfattning

Vid obduktion av ett rådjur och en älg påvisades ulcerativa och nekrotiserande skador i digestionskanalens slemhinnor. Både djuren hade antikroppar emot Bovin Virus Diarre. Histologiskt påvisades inter- och intracellulärt ödem i stratum germinativum och spinosum, vesikelbildning och ulceration r samt intracytoplasmatiska inklusionskroppar huvudsakligen i stratum germinativum.

Elektronmikroskopi bekräftade de histologiska fynden och inklusionskroppar innehållande ett kornigt elektron tätt material, omslutet av ett enskiktat membran. Virus partiklar kunde däremot ej påvisas.

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Authors and Affiliations

  1. The National Veterinary Institute, S-75007, Uppsala, Sweden

    R. Feinstein, C. Rehbinder, E. Rivera, T. Nikkilä & M. Steen

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  1. R. Feinstein
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  2. C. Rehbinder
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  3. E. Rivera
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  4. T. Nikkilä
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  5. M. Steen
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Feinstein, R., Rehbinder, C., Rivera, E. et al. Intracytoplasmic Inclusion Bodies Associated with Vesicular, Ulcerative and Necrotizing Lesions of the Digestive Mucosa of a Roedeer (Capreolus Capreolus L.) and a Moose (Alces Alces L.). Acta Vet Scand 28, 197–200 (1987). https://doi.org/10.1186/BF03548242

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Acta Veterinaria Scandinavica

ISSN: 1751-0147