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Some Effects of Protein Deficiency in Young Growing Pigs

I. The Serum Protein System

Acta Veterinaria Scandinavica volume 10, pages 382–401 (1969)Cite this article

Abstract

No significant differences between the serum protein concentrations of the totally starved pigs and control animals given a milk protein supplemented diet were found. Serum lipid levels rose in the totally starved group. During the first 42 days of the experimental period sharp falls in serum protein concentrations were noted in the protein deprived pigs. The losses were greatest in the albumin and two β-globulin fractions, γ-globulin levels rose but at a much slower rate than in the control group. In the pigs which were refed a protein containing diet during the second 42 day period, the concentrations of all the serum protein fractions except for γ-globulin had reached control levels by the end of the investigation. The pigs which continued with the protein free diet showed further losses of albumin, a reduction in some α-globulin fractions and a cessation of net γ-globulin synthesis. The trends observed by measurements of protein bound carbohydrate were similar to those obtained from polypeptide determinations indicating quantitative rather than qualitative changes in the serum proteins. The reduction in the serum lipid concentrations of the pigs undergoing protein starvation was largely accounted for by losses of α- and β-lipoproteins. The protein deprived pigs maintained their initial body weight, while a continuous fall in weight was found in the totally starved group and a continuous increase in the control pigs.

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Acknowledgments

The authors wish to thank Professor J. Moustgaard, Royal Veterinary and Agricultural University, Copenhagen, Denmark, for advice and encouragement, and colleagues in Zemun for useful discussions.

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Authors and Affiliations

  1. Institute for the Application of Nuclear Energy in Agriculture, Veterinary Medicine and Forestry, Zemun, Yugoslavia, Serbia

    J. A. Nikolić, M. Čuperlović & D. Stosić

  2. Department of Physiology, Endocrinology and Bloodgrouping, Royal Veterinary and Agricultural University, Copenhagen, Denmark

    J. A. Nikolić, M. Čuperlović & D. Stosić

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  1. J. A. Nikolić
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  2. M. Čuperlović
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  3. D. Stosić
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Nikolić, J.A., Čuperlović, M. & Stosić, D. Some Effects of Protein Deficiency in Young Growing Pigs. Acta Vet Scand 10, 382–401 (1969). https://doi.org/10.1186/BF03548271

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Acta Veterinaria Scandinavica

ISSN: 1751-0147