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The Metabolic Response to Norepinephrine in Carbon Tetrachloride Poisoned Sheep

Acta Veterinaria Scandinavica volume 10, pages 168–180 (1969)Cite this article

Abstract

The intraruminal administration of carbon tetrachloride to healthy sheep caused a sharp rise in the serum OCT levels. The plasma concentration of non-esterified fatty acids (NEFA) increased, while blood glucose remained unaffected. The glucose response to the intravenous injection of norepinephrine was greatly reduced after carbon tetrachloride administration, indicating a depletion of the liver glycogen. The NEFA response was not altered. As the increase in NEFA caused by carbon tetrachloride was only moderate, a block in lipoproteinsynthesis is discussed as the main factor in the development of the fatty liver.

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Authors and Affiliations

  1. Department of Medicine II, Royal Veterinary College, Stockholm, Sweden

    J. Luthman & G. Jonson

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  1. J. Luthman
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  2. G. Jonson
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Luthman, J., Jonson, G. The Metabolic Response to Norepinephrine in Carbon Tetrachloride Poisoned Sheep. Acta Vet Scand 10, 168–180 (1969). https://doi.org/10.1186/BF03548287

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  • DOI: https://doi.org/10.1186/BF03548287

Acta Veterinaria Scandinavica

ISSN: 1751-0147