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Necrotizing Infectious Enteritis in Piglets, Caused by Clostridium Perfringens Type C

Infektiøs nekrotiserende enteritis hos pattegrise forårsaget af Clostridium perfringens type C. IV. Bakteriologisk diagnose. Den diagnostiske signifikans af Clostridium perfringens type C blev belyst ved en undersøgelse for forekomst af denne clostridie i tarmindhold af 339 pattegrise med nekrotiserende enteritis og 121 pattegrise uden nekrotiske eller hæmorrhagiske forandringer i tyndtarmen

IV. Bacteriological Diagnosis

Acta Veterinaria Scandinavica volume 10, pages 84–100 (1969)Cite this article

Abstract

The diagnosis of necrotizing enteritis in infant piglets is based on clinical observations, patho-anatomical changes, and bacteriological and bacterio-toxicological examinations.

Previous works (Høgh 1967 a, b, 1969) have dealt with the aetiology, symptomatology and pathology of the disease.

The purpose of this paper is to present the results of bacteriological examinations of pigs from spontaneous outbreaks.

Sammendrag

Ved typebestemmelse af 1124 renkulturer blev Cl. perfringens type C påvist i tarmindhold af 301 pattegrise med nekrotiserende enteritis og i 9 pattegrise uden påviselige forandringer i tarmkanalen. Disse 9 pattegrise hidrørte alle fra besætninger, hvor sygdommen er konstateret (Tabel 2). Foruden Cl. perfringens type C forekom kun type A og ikke-nekrotiserende stammer (Tabel 3).

I hovedparten af tilfældene var infektionen lokaliseret til tarmkanalen og de mesenteriale lymfekirtler. I få tilfælde forekom Clostridien tillige i leveren (7,3 %) eller i milten (8,0 %), men kun i et enkelt tilfælde i begge organer samtidig (Tabel 5).

Cl. perfringens type C blev påvist med større hyppighed i tarmindhold af grise med hæmorrhagiske forandringer i tyndtarmen end hos grise med en voldsom nekrotiserende enteritis uden hæmorrhagi (Tabel 4). Det samme forhold gjorde sig gældende med hensyn til forekomst af β-toksin, som blev påvist i filtreret tarmindhold i 87 af 173 undersøgte prøver (Tabel 6). β-toksinet forekom i tarmindhold i ca. dobbelt så stor en mængde som i bughuleexsudat, mens brysthuleexsudat kun undtagelsesvis indeholdt påviselige mængder toksin (Tabel 7).

Isolation af renkulturer gav bedre diagnostiske resultater end påvisning af β-toksin i tarmindhold og i blandingskulturer fra dette (Tabel 8). Undersøgelse for forekomst af β-toksin er imidlertid et vigtigt supplement til den direkte udsæd på dextroseblodagar, ikke mindst i tilfælde, hvor en hurtig verifikation af diagnosen er ønskelig.

Hæmolytiske Escherichia coli og hæmolytiske streptococcer forekom i tarmindhold af 105 af 286 grise med nekrotiserende enteritis. Denne forekomst, der i hovedparten af tilfældene har været meget sparsom, må betragtes som tilfældig eller sekundær.

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Acknowledgments

The author is indebted to Mrs. I. Hansen, Mrs. V. Riis and Miss J. Weis for technical assistance.

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  1. State Veterinary Serum Laboratory, Copenhagen, Denmark

    Peter Høgh

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  1. Peter Høgh
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Høgh, P. Necrotizing Infectious Enteritis in Piglets, Caused by Clostridium Perfringens Type C. Acta Vet Scand 10, 84–100 (1969). https://doi.org/10.1186/BF03548298

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Acta Veterinaria Scandinavica

ISSN: 1751-0147