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An Outbreak of Septic Endometritis in the Arctic Blue Fox (Alopex Lagopus) caused by Clostridium Carnis
Et utbrudd av septisk endometritt hos blårev (Alopex lagopus) forårsaket av Clostridium carnis
Acta Veterinaria Scandinavica volume 29, pages 181–191 (1988)
Abstract
An outbreak of endometritis and septicaemia in farms that raise Arctic blue foxes is described. Eleven animals from eight different farms were examined, most of them pregnant or with newly delivered litters. Pathological examination indicated inflammation of the uterus, and focal necrotic changes in the liver. In some animals evidence of hemorrhaging was found in the anterior part of the small intestine. Bacteriological examination revealed abundant growth from different organs of the animals of a pure culture of a small, slender, Gram-variable, sporeforming rod, which was identified phenotypically as aerotolerant Clostridium carnis. This identification was confirmed by DNA hybridization. The organism caused death in mice 1–2 days after intraperitoneal inoculation, and killed an Arctic blue fox which was inoculated intracervically. Two foxes, pretreated with diethyl-stilboestrol, became seriously ill after intrauterine inoculation, but survived. The spontaneous outbreak of the disease was characterized by sudden onset of septicaemia with few or no clinical symptoms before the animals succumbed.
Sammendrag
Et utbrudd av endometritt og sepsis i blårevfarmer er beskrevet. Elleve dyr fra 8 forskjellige farmer ble undersøkt, de fleste av dem var drektige eller med nyfødte kull. Patologisk undersøkelse indikerte at det forelå betennelse i uterus i tillegg til fokale nekrotiske forandringer i leveren. Blodig innhold ble funnet i fremre del av tynntarmen hos noen dyr. Ved bakteriologisk undersøkelse ble en liten, slank, Gramvariabel, sporedannende stav som ble identifisert fenotypisk som den aerotolerante Clostridium carnis, påvist i stort antall og i renkultur fra forskjellige organer fra dyrene. Identifiseringen ble konfirmert ved hjelp av DNA hybridisering. Organismen drepte mus 1–2 dager etter intraperitoneal inokulasjon og blårev som ble inokulert intracervikalt. To rever som var behandlet med dietylstilbestrol på forhånd, ble alvorlig syke etter intrauterin inokulering, men overlevde. Få eller ingen kliniske symptomer ble registrert før dyrene ble funnet døende eller døde av oppdretterne.
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Sørum, H., Nordstoga, K., Loftsgaard, G. et al. An Outbreak of Septic Endometritis in the Arctic Blue Fox (Alopex Lagopus) caused by Clostridium Carnis. Acta Vet Scand 29, 181–191 (1988). https://doi.org/10.1186/BF03548369
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DOI: https://doi.org/10.1186/BF03548369