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Liquoid-Induced Arterial Lesions and the Generalized Shwartzman Reaction
Liquoid-induserte arterie-forandringer og den generaliserte Shwartzman’s reaksjon
Acta Veterinaria Scandinavica volume 18, pages 515–521 (1977)
Abstract
Mural necrotic lesions were produced in renal afferent arteries in rabbits, pigs and blue foxes, by intravenous injections of Liquoid. These lesions were frequently accompanied by thrombosis in the affected arterial segments and invariably by “microthrombosis” in glomerular capillaries. Mural arterial lesions were always present in cases with evident macroscopic necrotic changes of the renal cortex. Necrotic arterial lesions, with thrombosis, were also observed in pulmonary arteries in all the animal species used in these experiments, i.e. rabbit, pig, blue fox, mouse and ferret.
Sammendrag
Ved intravenøse injeksjoner av Liquoid ble det framkalt nekrotiserende forandringer i afferente nyrearterier hos kanin, gris og blårev. Forandringene var ledsaget av „mikrotromber“ i kapillærene i glomeruli, og ofte også av tromboseringer i de affiserte segmenter av arteriene. Karveggsf oran dringer var alltid tilstede når det forelå makroskopiske, nekrotiske forandringer i nyrebarken. Nekrotiserende forandringer med tromboseringer, ble observert i lungearterier hos alle dyrearter undersøkelsen omfattet, dvs. kanin, gris, blårev, mus og fritte.
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Nordstoga, K. Liquoid-Induced Arterial Lesions and the Generalized Shwartzman Reaction. Acta Vet Scand 18, 515–521 (1977). https://doi.org/10.1186/BF03548415
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DOI: https://doi.org/10.1186/BF03548415