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Endotoxins in Animal Feedstuffs
Acta Veterinaria Scandinavica volume 18, pages 566–568 (1977)
Abstract
Microbial heat stable endotoxins comprise part of most animal feedstuffs. These components have become the subject of considerable interest in later years because of the demonstration of acute toxicity, intravascular coagulation and generalized Shwartzman’s reaction in connection with intravenous injections of endotoxins (Nordstoga 1976). Endotoxins are normally present in the intestine of man and animals, but seem only to be absorbed under special conditions. Of particular interest is the “sudden infant death syndrome” which has been described for infants receiving cow milk (Di Luzio & Friedmann 1973). Absorption of endotoxins may also occur in adults e.g. in connection with γ-irradiation, immunosuppression, transplantations, severe traumatic lesions and burns (Nordstoga). It is supposed that endotoxins play an important role in the development of shock under these conditions (Nordstoga). Fine (1972) reported that exogenously administered endotoxins may break down the defence mechanisms and lead to continuous absorption of endotoxins from the intestine.
References
Børresen B.: Pyometra in the dog - A pathophysiological investigation. I. The pyometra syndrome, a review. Nord. Vet.-Med. 1975, 27, 508–517.
Grindlay M. J. P. Renton & D. H. Ramsay: O-groups of Escherichia coli associated with canine pyometra. Res. Vet. Sci. 1973, 14, 75–77.
Hinshaw L. B.: Release of vasoactive agents and the vascular effects of endotoxin. In Microbial Toxins. Vol. 5. S. Kadis, G. Weinbaum and S. J. Ajl, eds., Acad. Press, New York 1971, 209–260.
Krogstad O.: Yersinia enterocolitica infection in goat. A serological and bacteriological investigation. Acta vet. scand. 1974, 15, 597–608.
Moravek J. Z. Konikova, J. Sedlak & V. Matejicek: Detection of endotoxin in human plasma. J. Hyg. Epidem. (Praha) 1974, 18, 462–464.
Rutenburg S. R. Skarnes, C. Palmerio & J. Fine: Detoxification of endotoxin by perfusion of liver and spleen. Proc. Soc. exp. Biol. (N. Y.) 1967, 125, 455–459.
Sandholm M. H. Vasenius S: A.-K. Kiuistø: Pathogenesis of canine pyometra. J. Amer. vet. med. Ass. 1975, 167, 1006–1010.
Schalm O. W.: Pyometra in the dog. Degenerative left shift in pyometra. In Schalm, O. W.: Veterinary Hematology. 2nd Ed. Lea & Febiger, Philadelphia 1965, 559–560.
Ăsheim Ă.: Renal function in dogs with pyometra. 8. Uterine infection and the pathogenesis of the renal dysfunction. Acta path, microbiol. scand. 1964, 60, 99–107.
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Nœss, B., Korvald, B. & Sandvik, O. Endotoxins in Animal Feedstuffs. Acta Vet Scand 18, 566–568 (1977). https://doi.org/10.1186/BF03548422
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DOI: https://doi.org/10.1186/BF03548422