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Experimental Anaphylaxis in Pigs
Eksperimentell anafylaksi hos yris. Betydningen av forets vitamin E- innhold
The Influence of the Vitamin E Content in the Feed
Acta Veterinaria Scandinavica volume 18, pages 210–220 (1977)
Abstract
An anaphylactic reaction was provoked in pigs by two intravenous injections of chicken egg albumin given approx. 2 weeks apart; some of the animals were in a state of vitamin E deficiency. The second injection of albumin was followed by vomiting, forced respiration, severe cyanosis and distinct edema in the stomach, larynx and gall bladder. These pathomorphological changes are in accordance with those regarded as typical for edema disease. Both the clinical symptoms and the pathomorphological alterations were most evident in animals with vitamin E supplementation, whereas vitamin E deficient animals showed a more moderate response. The anaphylactic reaction was not accompanied by evident changes resembling Mulberry heart disease, either in normal pigs or in vitamin E deficient animals.
Sammendrag
En anafylaktisk reaksjon ble fremkalt hos gris ved hjelp av to intravenøse injeksjoner av kyllingegg-albumin, gitt med ca. 14 dagers mellomrom. Endel av forsøksdyrene led av vitamin E-mangel. Den andre injeksjonen av albumin ble fulgt av oppkast, respirasjonsbesvær, tydelig cyanose og ødemer i ventrikkel, larynx og galleblære. De pato- morfologiske forandringer er i samsvar med det som angis å være typisk for ødemsyke. Både kliniske symptomer og de patomorfologiske forandringer var tydeligst hos de dyrene som fikk vitamin E-tilskudd, mens vitamin E-mangel-dyrene viste en mer moderat reaksjon. Den anafylaktiske reaksjon ble ikke ledsaget av tydelige morfologiske forandringer av den type som sees ved akutt hjertedød, hverken hos normale griser eller hos dyr med vitamin E-mangel.
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Teige, J., Nordstoga, K. Experimental Anaphylaxis in Pigs. Acta Vet Scand 18, 210–220 (1977). https://doi.org/10.1186/BF03548449
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DOI: https://doi.org/10.1186/BF03548449