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Susceptibility of Foxes to Clostridium Botulinum Type C and E Toxins

Acta Veterinaria Scandinavica volume 18, pages 23–30 (1977)Cite this article

Abstract

Investigations were performed to determine the exact susceptibility of foxes to Clostridium botulinum type C and E toxins.

Doses of 5 mill. MLD type C toxin mixed with the feed did not cause symptoms of botulism in either cubs or adult foxes. Subcutaneous injections of 300,100(0 MLD or more were fatal to cubs, while 750,000 MLD caused the death of all adults.

Regarding type E toxin, doses of 1 mill. MLD affected neither cubs nor adults on oral administration. Subcutaneously injected doses of 5,000 MLD or more killed all cubs, while 10,000 MLD was required to produce lethal effect on adult animals.

The conclusion made is that foxes are highly resistant to both type C and E Clostridium botulinum toxins following oral application. It is further revealed that foxes are 60–70 times more susceptible to type E than to type C toxin when injected subcutaneously.

References

  • Dinter, Z. & K. E. Kull: Botulismus beim Nerz in Schweden. (Botulism in mink in Sweden). Nord. Vet-Med. 1950, 2, 286–301.

    Google Scholar 

  • Dinter, Z. & K. E. Kull: Uber die Empfanglichkeit des Nerzes fur die Botulinus-Toxine A und G. (The susceptibility of mink to botulinum toxins A and C). Nord. Vet.-Med. 1955, 7, 549–563.

    Google Scholar 

  • Graham, R. & S. Erikson: Experimental botulism in dogs. J. infect. Dis. 1922, 31, 402–406.

    Article  Google Scholar 

  • Gustavsen, S., S. Hauge, G. Loftsgdrd, T. Oftebro, L. Rossebfi, T. B. Tjaberg & T. Aaneland: Repeated botulism outbreaks in mink caused by feed from a central processing plant. Ganad. vet. J. 1969, 10, 244–247.

    CAS  Google Scholar 

  • Hall, I. C. & G. W. Stiles: An outbreak of botulism in captive mink on a furfami in Colorado. J. Bact. 1938, 36, 282.

    Google Scholar 

  • Johannsen, A.: Botulisme hos hund. (Botulism in dogs). Nord. Vet.- Med. 1965, 17, 680–684.

    Google Scholar 

  • Kennedy, A. H.: Mink and fox diseases in Ontario. Rep. Ontario Vet. Goll., Toronto, Canada 1946, 47, 98–105.

    Google Scholar 

  • Kull, K. E. & K. Moberg: Die Haufigkeit des Botulismus bei Fiitter- vergiftungen des Nerzes in Schweden 1951. (The frequency of food poisonings caused by botulism in minks in Sweden in 1951). Nord. Vet.-Med. 1921, 4, 771–775.

    Google Scholar 

  • Legroux, E. & J. C. Levaditi: Le botulisme experimental du chien et la question du botulisme naturelie. (Experimental and possible naturally occurring botulism in dogs). Ann. Inst Pasteur 1947, 73, 105–415.

    Google Scholar 

  • Nordstoga, K.: Mistanke om botulisme i en blarevbesetning. (Suspected occurrence of botulism in a blue fox farm). Norsk Vet.-T. 1973, 85, 654–655.

    Google Scholar 

  • Pyle, N. J. & R. M. Brown: Botulism in foxes. J. Amer. vet. med. Ass. 1939, 94, 436–439.

    Google Scholar 

  • Quortrup, E. R. & J. R. Gorham: Susceptibility of furbearing animals to the toxins of Clostridium botulinum types A, B, C and E. Amer. J. vet. Res. 1949, 10, 263–2l71.

    Google Scholar 

  • Quortrup, E. R. & A. L. Holt: A case report on botulism type C in mink. J. Amer. vet. med. Ass. 1940, 97, 167–168.

    Google Scholar 

  • Skulberg, A.: Botulisme hos mink. (Botulism in mink). Medlemsbl. norske Vet.-Foren. 1957, 9, 41–48.

    Google Scholar 

  • Skulberg, A.: Botulism in mink caused by Clostridium botulinum type E. Nord. Vet.-Med. 1961, 13, 87–95.

    Google Scholar 

  • Skulberg, A. & M. Valland: Susceptibility of mink to Clostridium botulinum type E toxin. Acta vet. scand. 1969, 10, 137–145.

    CAS  PubMed  PubMed Central  Google Scholar 

  • Tjaberg, T. B. & A. Skulberg: Minks mottagelighet for Clostridium botulinum type C toksin. (Susceptibility of mink to Clostridium botulinum type C toxin). Nord. Vet.-Med. 1968, 20, 313–318.

    Google Scholar 

  • Vallee, A., A. Kreguer & A. Egquem: Botulisme canin: Premiere souche isole en France. (Botulism in dogs. The first case reported in France). Bull. Acad. vet. Fr. 1956, 29, 419–423.

    Google Scholar 

  • Vndestad, M. & G. Loftsgard: Susceptibility of mink to Clostridium botulinum type C toxin. Acta vet. scand. 1970, 11, 594–599.

    Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Food Hygiene and the Research Station for Furbearing Animals, Veterinary College of Norway, P. O. Box 8146, Oslo Dep., Oslo 1, Norway

    Magne Yndestad, Arne Helgebostad & Gudbrand Loftsgård

  2. Norwegian Fur Farmers Research Laboratory, Oslo, Norway

    Magne Yndestad, Arne Helgebostad & Gudbrand Loftsgård

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  1. Magne Yndestad
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  2. Arne Helgebostad
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  3. Gudbrand Loftsgård
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Yndestad, M., Helgebostad, A. & Loftsgård, G. Susceptibility of Foxes to Clostridium Botulinum Type C and E Toxins. Acta Vet Scand 18, 23–30 (1977). https://doi.org/10.1186/BF03548462

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Acta Veterinaria Scandinavica

ISSN: 1751-0147