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The Mechanism of Excretion of Drugs into Milk from Untreated Glands after Intramammary Application
Acta Veterinaria Scandinavica volume 13, pages 275–277 (1972)
Abstract
It is often maintained that after intramammary application of penicillin the excretion of penicillin via the untreated glands takes place by direct diffusion from treated to untreated glands (vide Hawkins et al. 1962, Jacobs & Pennings 1969, Rollins et al. 1970). Blobel (1960) mentions the possibilities of both direct diffusion from gland to gland and the excretion via the blood.
References
Blobel, H.: Concentration of penicillin in milk secretions and blood serums of cows following intramammary infusion of one or more quarters. J. Amer. vet. med. Ass. 1960, 137, 110–113.
Hawkins, G. E., R. Y. Cannon & G. E. Paar: Concentration of penicillin in milk from noninfused quarters following infusion of one quarter. J. Dairy Sci. 1962, 45, 1020–1022.
Jacobs, J. & A. Pennings: Antibiotic residues in milk of cows after infusion of so called quick release mastitis agents. T. Dier- geneesk. 1969, 94, 1305–1317.
Rasmussen, Folke: Distribution of sulphonamides in the mammary gland of cows after intramammary and intravenous application. Acta vet. scand. 1964, 5, 347–361.
Rasmussen, Folke: Studies on the mammary excretion and absorption of drugs. Thesis, C. Fr. Mortensen, Copenhagen 1966.
Rasmussen, Folke: Excretion of drugs by milk. In Handbook of Experimental Pharmacology. Springer-Verlag, Berlin, New York 1971, 48: 1, 390-402.
Rollins, L. D., H. D. Mercer, G. G. Carter & J. Kramer: Absorption, distribution and excretion of penicillin and dihydrostreptomycin in dairy cows following intramammary infusion. J. Dairy Sci. 1970, 53, 1407–1414.
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Rasmussen, F. The Mechanism of Excretion of Drugs into Milk from Untreated Glands after Intramammary Application. Acta Vet Scand 13, 275–277 (1972). https://doi.org/10.1186/BF03548585
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DOI: https://doi.org/10.1186/BF03548585