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The Effects of Sugar Alcohols on Metabolism of Growing Pigs

Effekten av sockeralkoholer på ämnesomsättningen hos växande grisar

Abstract

In two experiments of 3 × 3 Latin square with growing pigs, the effect was investigated of supplementation of 5 % or 10 % (2.5 % vs. 5 % DM) polyol mixture and 2.5 % or 5 % of xylitol on digestibility of diet, N-balance, blood clinical-chemical parameters and insulin level in serum. Apparent digestibility of crude protein was lower for the diet with 10 % polyol mixture compared to the control. Sugar alcohols were not found in faeces. Arabinitol, mannitol and rhamnitol were excreted in the urine 25–67 %. Little sorbitol and xylitol were found in urine on diets with polyol mixture 5–10 %. On xylitol diets the pigs did not excrete xylitol in urine. Plasma glucose rose in pigs fed xylitol. Blood total protein and albumin decreased in pigs fed polyol mixture. ALAT-activities were higher for xylitol diets than for the controls. Serum insulin tended to increase in pigs fed polyol mixture 10 % one hour after feeding, and in xylitol feeding two hours after feeding; these values were higher with increasing xylitol inclusion in diet.

Sammanfattning

I två försök med växande grisar med en utfodring enligt 3×3 latinsk kvadrat undersöktes effekten av en tillsats av 5 % eller 10 % (2.5 eller 10 % DM) polyol-blandning, samt 2.5 % eller 5 % xylitol på fodrets smältbarhet, N-balansen, klinisk-kemiska blodparametrar och insulinstatus i serum. Råproteinets smältbarhet verkade vara lägre med ett foder innehållande 10 % polyol-blandning än med kontrollfodret. Sockeralkoholer kunde inte påvisas avföringen. Arabinitol, mannitol och rhamnitol utsöndrades till 25–67 % med urinen. Endast litet sorbitol och xylitol kunde påvisas i urinen vid en diet med en 5–10 % polyol-blandning. Vid en xylitol-diet utsöndrade grisarna inget xylitol med urinen. Glukos i blodplasma steg hos grisar utfodrade med xylitol. Blodproteinet och -albuminet sjönk hos grisar utfodrade med en polyol-blandning. ALAT-värdena var högre vil xylitol-dieter jämfört med kontrollen. En timme efter utfodring med en 10 % polyolblandning visade insulinet i serum en tendens att öka. Vid xylitolutfodring var dessa värden två timmar efter utfodringen allt högre, följande ökande tillsatser av xylitol i fodret.

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Näsi, M., Tanhuanpää, E. The Effects of Sugar Alcohols on Metabolism of Growing Pigs. Acta Vet Scand 22, 344–354 (1981). https://doi.org/10.1186/BF03548659

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