Skip to main content
  • Published:

The Immediate Effect of HCG Upon Plasma Testosterone Levels in the Bull

Den øyeblikkelige effekt av HCG på plasma testosteron nivå hos okse

Abstract

No effect of HCG upon the plasma testosterone level in 16 bulls was seen the first 5 or 15 min after injection. In 8 bulls receiving 750 or 1500 i.u. HCG by intravenous injection a lag time of 30 min occurred before plasma testosterone response could be measured. The high plateau level of plasma testosterone concentration was reached approximately 1 h after injection.

Following intramuscular injection of 750 i.u. or 1500 i.u. HCG a lag time of 45–60 min was observed for the testicular response measured as elevated plasma testosterone level. The high plateau levels of plasma testosterone in these bulls were reached approximately 1½ h post injection.

Sammendrag

Ingen effekt av HCG på plasma testosteron nivået hos 16 okser kunne påvises de første 5 eller 15 minutter etter injeksjonen. Hos 8 okser som fikk 750 eller 1500 i.u. HCG ved intravenøs injeksjon varte det 30 minutter før en økning av plasma testosteron nivået kunne påvises. Høyt, stabilt plasma testosteron nivå kom ca. 1 time etter injeksjonen.

Etter intramuskulær injeksjon av 750 eller 1500 i.u. HCG ble det observert en ventetid på 45–60 minutter før testikulær respons målt som øket plasma testosteron nivå. Høyt, stabilt plasma testosteron hos disse oksene ble målt ca 1½ time etter injeksjonen.

References

  • Andresen, Ø.: 5α-androstenone in peripheral plasma of pigs, diurnal variation in boars, effects of intravenous HGG administration and castration. Acta endocr. (Kbh.) 1975, 78, 385–391.

    CAS  Google Scholar 

  • Bartke, A., R. E. Steele, N. Musto & B. V. Caldwell: Fluctuations in plasma testosterone levels in adult male rats and mice. Endocrinology 1973, 92, 1223–1227.

    Article  CAS  Google Scholar 

  • Boyden, T. W., R. W. Pamenter & M. A. Siluert: Testosterone secretion by the isolated canine testis after controlled infusions of HCG. J. Reprod. Fertil. 1980, 59, 25–30.

    Article  CAS  Google Scholar 

  • Brinck-Johnsen, T. & K. B. Eik-Nes: Effect of human chorionic gonadotropin on the secretion of testosterone and 4-androstene-3, 17-dione by the canine testis. Endocrinology 1957, 61, 176–683.

    Article  Google Scholar 

  • DePalatis, L., J. Moore & R. E. Falvo: Plasma concentrations of testosterone and LH in the male dog. J. Reprod. Fertil. 1978, 52, 201–207.

    Article  CAS  Google Scholar 

  • Eik-Nes, K. B.: Factors influencing the secretion of testosterone in the anaesthetized dog. Ciba Found. Golloq. Endocrinol. (Proc) 1967, 16, 120–136.

    CAS  Google Scholar 

  • Foster, D. L., I. H. Mickelson, K. D. Ryan, G. A. Coon, R. A. Drongowski & J. A. Holt: Ontogeny of pulsatile luteinizing hormone and testosterone secretion in male lambs. Endocrinology 1978, 102, 1137–1146.

    Article  CAS  Google Scholar 

  • Katongole, C. B., F. Naftolin & R. V. Short: Relationship between blood levels of luteinizing hormone and testosterone in bulls and the effect of sexual stimulation. J. Endocr. 1971, 50, 457– 466.

  • Katongole, C. B., R. V. Short & F. Naftolin: Plasma luteinizing hormone and testosterone in the ram. J. Endocr. 1972, 52, 52–111.

    Google Scholar 

  • Lincoln, G. A.: Plasma testosterone profiles in male macropodid marsupials. J. Endocr. 1978, 77, 347–351.

    Article  CAS  Google Scholar 

  • Moor, B. C. & E. V. Younglai: Variations in peripheral levels of LH and testosterone in adult male rabbits. J. Reprod. Fert. 1975, 42, 259–266.

    Article  CAS  Google Scholar 

  • Purvis, K., A. W. Illius & N. B. Haynes: Plasma testosterone concentrations in the ram. J. Endocr. 1974, 61, 231–253.

    Article  Google Scholar 

  • Rowe, P. H., C. R. N. Hopkinson, J. C. Shenton & T. D. Glover: The secretion of LH and testosterone in the rabbit. Steroids 1975, 25, 313–321.

    Article  CAS  Google Scholar 

  • Rowe, P. H., G. A. Lincoln, P. A. Racey, J. Lehane, M. J. Stephenson, J. C. Shenton & T. D. Glover: Temporal variations of testosterone levels in the peripheral blood plasma of men. J. Endocr. 1974, 61, 63–73.

    Article  CAS  Google Scholar 

  • Sand, T. & P. A. Torjesen: Dextran-coated charcoal used in the radioimmunoassay of human pituitary luteinizing hormone. Acta endocr. 1973, 73, 444–454.

    CAS  PubMed  Google Scholar 

  • Sanwal, P. C., A. Sundby & L. E. Edqvist: Diurnal variation of peripheral plasma levels of testosterone in bulls measured by a rapid radioimmunoassay procedure. Acta vet. scand. 1974, 15, 90–99.

    Article  CAS  Google Scholar 

  • Sundby, A.: The immediate effect of HGG upon plasma testosterone levels in the bull. Acta vet. scand. 1981, 22, 403–408.

    CAS  PubMed  Google Scholar 

  • Sundby, A. & A. Farahat: Plasma testosterone in bulls: Response to various doses of HGG and PMSG. Acta endocr. 1978, 88, 793– 800.

  • Sundby, A. & P. A. Torjesen: Plasma levels of testosterone in bulls: Response to repeated HCG injections. Acta endocr. 1978, 88, 787–792.

    CAS  PubMed  Google Scholar 

  • Sundby, A. & W. Velle: Plasma concentration of testosterone in young bulls in relation to age, rate of weight gain and stimulation with human chorionic gonadotropin. J. Endocr. 1980, 86, 465– 469.

  • Sundby, A., R. Tollman & W. Velle: Long-term effect of HCG on plasma testosterone in bulls. J. Reprod. Fertil. 1975, 45, 249–254.

    Article  CAS  Google Scholar 

  • Thibier, M.: Diurnal testosterone and 17α-hydroxyprogesterone in peripheral plasma of young post-pubertal bulls. Acta endocr. 1976, 81, 623–634.

    CAS  PubMed  Google Scholar 

  • Wilson, M. I., G. M. Brown & D. Wilson: Annual and diurnal changes in plasma androgen and Cortisol in adult male squirrel monkeys (Saimiri sciureus) studied longitudinally. Acta endocr. 1978, 87, 424–434.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

The investigation was financially supported by the Agricultural Research Council of Norway.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sundby, A. The Immediate Effect of HCG Upon Plasma Testosterone Levels in the Bull. Acta Vet Scand 22, 403–408 (1981). https://doi.org/10.1186/BF03548665

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1186/BF03548665

Keywords