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Immunoglobulin Levels in Non-Aborted and Aborted Fetuses from Danish Herds of Cattle

Immunoglobulin niveau hos ikke-aborterede og aborterede fostre fra danske kvægbesætninger

Abstract

The applicability of serological tests in the diagnosis of intrauterine infections in Danish cattle was investigated. Fetuses from slaughter animals, experimentally infected and spontaneously aborted fetuses, premature and stillborn calves, were subjected to necropsy and histological studies, and to microbiological and serological examinations. The latter comprised rocket immunoelectrophoresis and radial immunodiffusion. In sera of the fetuses from slaughter animals, immunoglobulins were either not detectable or only present in very small quantities, whereas sera of fetuses and calves with pathological changes and/or verified infection contained considerable amounts of IgM and IgG. IgA was also detected in the latter group. The results corroborate the diagnostic importance of immunoglobulin determination in aborted fetuses and stillborn calves.

Sammendrag

Anvendeligheden af serologiske tests, som et bidrag til diagnostisering af intrauterine infektioner, blev undersøgt på et dansk kvægmateriale. Fostre fra slagtekvæg, eksperimentelt inficerede og spontant aborterede fostre samt præmature og dødfødte kalve blev underkastet makro- og mikroskopiske, mikrobiologiske og serologiske undersøgelser. Sidstnævnte omfattede raket immunoelektroforese og radial immun diffusion.

Immunoglobulin er var kun påviselige i små mængder hos ganske få fostre fra slagtekvæg, mens sera fra fostre og kalve med patologiske forandringer og/eller verificeret infektion indeholdt betydelige mængder IgM og IgG. IgA kunne også påvises i sera fra denne individgruppe. Resultaterne viser den diagnostiske betydning af en immunoglobulinbestemmelse for aborterede fostre og dødfødte kalve.

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Ohmann, H.B. Immunoglobulin Levels in Non-Aborted and Aborted Fetuses from Danish Herds of Cattle. Acta Vet Scand 22, 428–434 (1981). https://doi.org/10.1186/BF03548668

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