Skip to main content
  • Published:

Seroprevalence of Border Disease in Danish Sheep and Goat Herds

Seroprævalens of Border Disease i danske fåre- og gedebesætninger

Abstract

A study was conducted in 1994–96 with the aim of assessing the serological prevalence of Border Disease (BD) among sheep and goats in Denmark and to investigate possible relations to herd factors. From each of 1000 herds, 2 blood samples were obtained from animals older than 1 year. The examination for antibodies was performed using a blocking ELISA detecting antibodies to pestivirus. Data from 815 herds were analysed statistically by the maximum likelihood method in a multinomial model. The estimated herd prevalence was 0.083 and the estimated individual prevalence within the positive herds was 0.50. There was no difference between the prevalence in sheep and goat herds. Records for well over half of the herds could be combined with data from the Danish Central Husbandry Register. No association between occurrence of BD and herd size was found. Cattle were registered as contemporarily present on 135 out of 521 herds – which was shown to be strongly associated to BD. The estimated herd prevalences of BD among farms with and without contemporary cattle were 0.24 and 0.042, respectively.

Sammendrag

En undersøgelse udførtes i 1994–96 med det formål at bestemme den serologiske prævalens af Border disease (BD) blandt fåre- og gedebesætninger i Danmark, samt at belyse mulige sammenhænge med forskellige besætningsfaktorer. Fra 1000 besætninger blev der udtaget to blodprøver af dyr, som var ældre end 1 år. Undersøgelse for antistoffer blev foretaget ved blokerings-ELISA. Data blev analyseret statistisk ved hjælp af maksimum likelihood metoden i en multinomialfordeling. Den estimerede besætningsprævalens var 0.083, og den individuelle prævalens proportion i positive besætninger blev estimeret til 0.50. Der kunne ikke påvises nogen forskel på fåreog gedebesætninger.

For godt halvdelen af besætningerne kunne data kombineres med et udtræk fra CHR-registeret. Der kunne ikke vises nogen sammenhæng mellem forekomst af BD og besætningsstørrelse. Samtidigt kvæghold i besætningen var registreret på 135 ud af 521 besætninger, og data tydede på en klar sammenhæng mellem kvæghold og forekomst af BD. Den estimerede besætningsprævalens blandt besætninger med og uden kvæghold var henholdsvis 0.24 og 0.042.

References

  • Bitsch V, Rønsholt L: Control of bovine viral diarrhoea virus infection without vaccines. Vet. Clin. North. Am. Food. Anim. Prac. 1995, 11, 627–640.

    Article  CAS  Google Scholar 

  • Christensen J, Gardner I: Herd-level interpretation of test results for epidemiological studies of animal diseases. Prev. Vet. Med. 2000, 45, 83–106.

    Article  CAS  Google Scholar 

  • Cox DR, Hinkley DV: Theoretical Statistics. London, Chapman and Hall, 1974.

    Book  Google Scholar 

  • Frost JW, Westphäling I, Krauss H: Detection of the prevalence of antibodies against Border disease in sheep in south and central Hessen (Germany). Tierarztl. Umschau 1991, 46, 533–535.

    Google Scholar 

  • Lundén A, Carlsson U, Näslund K: Toxoplasmosis and Border disease in 54 Swedish sheep flocks. Seroprevalence and incidence during one gestation period. Acta. Vet. Scand. 1992, 33, 175–184.

    Google Scholar 

  • Løken T: Border disease in sheep. Vet. Clin. North. Am. Food. Anim. Prac. 1995a, 11, 579–596.

    Article  Google Scholar 

  • Løken T: Ruminant pestivirus infections in animals other than cattle and sheep. Vet. Clin. North. Am. Food. Anim. Prac. 1995b, 11, 597–614.

    Article  Google Scholar 

  • Løken T, Krogsrud J, Larsen IL: Pestivirus infections in Norway. Serological investigations in cattle, sheep and pigs. Acta. Vet. Scand. 1991, 32, 27–34.

    Article  Google Scholar 

  • Murphy FA, Fauquet CM, Bishop DHL, Ghabrial SA, Jarvis AW, Martelli GP, Mayo MA, Summers MD (eds.): Virus Taxonomy: The Sixth Report of the International Committee on Taxonomy of Viruses. Springer Verlag, Wien, 1995.

  • Nettleton PF, Gilray JA, Russo P, Dlissi E: Border disease of sheep and goats. Vet. Rec. 1998, 29, 327–340.

    CAS  Google Scholar 

  • Venzon DJ & Moolgavkar SH: A method for computing profile-likelihood-based confidence intervals. Appl. Statist. 1988, 37, 87–94.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to H. Stryhn.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Tegtmeier, C., Stryhn, H., Uttenthal, Å. et al. Seroprevalence of Border Disease in Danish Sheep and Goat Herds. Acta Vet Scand 41, 339–344 (2000). https://doi.org/10.1186/BF03549624

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1186/BF03549624

Keywords