Figure 6

Histological and immunohistochemical findings. Histological and immunohistochemical findings in a Brown Swiss heifer with lymphoma of the right nasal cavity. A) Monomorph population of small lymphoid cells containing a round nucleus with one nucleolus and stippled chromatin surrounded by a thin rim of pale eosinophilic cytoplasm. Single cells have hyperchromatic nuclei, nuclear indentation and mild anisokaryosis. H&E staining, 100x. B) The majority of neoplastic cells are positive for the T-cell marker CD3. C) 55% of the neoplastic cells express the proliferation marker Ki-67.