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Fig. 6 | Acta Veterinaria Scandinavica

Fig. 6

From: Pulmonary veno-occlusive disease as a cause of severe pulmonary hypertension in a dog

Fig. 6

Histologic appearance of the lungs demonstrating remodelling of pulmonary venules. a Normal pulmonary architecture. Circle: alveolus, asterisk: lumen of vein, arrow: normal capillary with endothelial cells and erythrocytes. Hematoxylin and eosin. b Pulmonary venule with severe intimal fibrosis and obliteration of the lumen (asterisk) with adjacent focus of pulmonary capillary hemangiomatosis (PCH) (arrowhead). Hematoxylin and eosin. c Transverse image of a remodeled inter-alveolar pulmonary venule with severe obliteration of the lumen (asterisk) and changes suggestive of post-thrombotic recanalization. The identity of the vessel as a vein was confirmed by the presence of a single external elastic lamina (arrow). Weigert’s resorcine fuchsine. d Longitudinal image of an abnormal pulmonary venule with remodeling and severe obliteration of the tortuous lumen (asterisk). The identity of the vessel as a vein was confirmed by the presence of a single external elastic lamina (arrow). The arrowheads indicate foci of PCH. Weigert’s resorcine fuchsine

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