Fig. 4

Neuroma from gelding (no. 15). a Irregular neural proliferation of variable-sized micro-fascicles with axonal sprouts in fibrous connective tissue (HE). An area infiltrated with inflammatory cells (neutrophils, lymphocytes and macrophages). b The axonal sprouts identified by immuno-staining with antibodies against NSE (brown color). c These show no staining when incubated with the non-specific IgG