Fig. 1

Photomicrographs of cerebellar lesions. a Cytoplasmatic remnants of a Purkinje cell are seen within an empty basket (arrowhead), while another degenerated Purkinje cell has pale cytoplasm, a large pale nucleus and poorly defined borders (arrow); b Shrunken Purkinje cells with sparse amounts of cytoplasm (arrows); c Immunohistochemical staining for glial fibrillary acidic protein showing astrogliosis in the Purkinje cell layer (arrows). Bar = 20 µm; a-b: hematoxylin and eosin; c: UltraVision HRP